Antidepressants may narrow the arteries of middle-aged men, potentially putting them at risk for heart attacks and stroke, researchers said.
A study involving 513 male twins, with an average age of 55, found those who took medications like Forest Laboratories Inc. (FRX)’s Lexapro, Eli Lilly & Co. (LLY)’s Cymbalta or Pfizer Inc. (PFE)’s Zoloft had thicker blood vessel walls. The increase, a measure of fatty-plaque buildup linked to atherosclerosis, was seen regardless of what type of antidepressant the men were taking.