Common painkillers such as ibuprofen and diclofenac as well as branded pain drugs from Pfizer Inc, Merck & Co Inc and Novartis AG can increase the risk of heart attacks and strokes, a review found on Wednesday.
Scientists from Bern University in Switzerland analyzed data from 31 trials involving more than 116,000 patients taking either naproxen, ibuprofen, diclofenac, Pfizer's Celebrex, or celecoxib, Merck's Arcoxia, or etoricoxib, Merck's Vioxx, or rofecoxib, Novartis' Prexige, or lumiracoxib, or a placebo, to try to give an estimate of the heart risks of such medicines.
Analysis shows heart, stroke risk of pain drugs
Lies, Damned Lies, and Medical Science
Much of what medical researchers conclude in their studies is misleading, exaggerated, or flat-out wrong. So why are doctors—to a striking extent—still drawing upon misinformation in their everyday practice? Dr. John Ioannidis has spent his career challenging his peers by exposing their bad science.
But beyond the headlines, Ioannidis was shocked at the range and reach of the reversals he was seeing in everyday medical research. “Randomized controlled trials,” which compare how one group responds to a treatment against how an identical group fares without the treatment, had long been considered nearly unshakable evidence, but they, too, ended up being wrong some of the time. “I realized even our gold-standard research had a lot of problems,” he says. Baffled, he started looking for the specific ways in which studies were going wrong. And before long he discovered that the range of errors being committed was astonishing: from what questions researchers posed, to how they set up the studies, to which patients they recruited for the studies, to which measurements they took, to how they analyzed the data, to how they presented their results, to how particular studies came to be published in medical journals.
A fat tummy shrivels your brain
HAVING a larger waistline may shrink your brain.
Obesity is linked to an increased risk of type 2 diabetes, which is known to be associated with cognitive impairment. So Antonio Convit at the New York University School of Medicine wanted to see what impact obesity had on the physical structure of the brain. He used magnetic resonance imaging to compare the brains of 44 obese individuals with those of 19 lean people of similar age and background.
Popular Cancer Drug Declared More Harmful Than Helpful
The FDA has said that the controversial drug Avastin should be phased out as a treatment for metastatic breast cancer. Recent studies show that its benefits are outweighed by dangerous side effects.
The announcement does not affect Avastin's status as a drug that can be prescribed for lung cancer, kidney cancer, colorectal cancer and brain cancer.
"Along with those disappointing findings, serious side effects became apparent in patients taking Avastin, including high blood pressure, internal bleeding, perforated internal organs, heart failure and heart attacks, and in some cases, even swelling of the brain."
Urgent action needed to help stop fluoridation of New York City and San Diego
There's good news on the fluoride front in New York City this week, but your help is needed there (and also in San Diego). Councilor Peter Vallone is introducing a bill to the New York City Council that would end fluoridation in NYC. We need help from all our New York City readers to support this effort to protect the safety of the NYC water supply and remove this toxic chemical from the tap water there.
Fluoride is a poison
Autism study doctor a 'victim of smear campaign'
The doctor who linked childhood autism to a vaccine and has been branded a fraud by the British Medical Journal (BMJ) said he was the victim of a smear campaign by drug manufacturers.
Andrew Wakefield was barred from medical practice last year after the General Medical Council in London found him guilty of "unethical" research that sparked unfounded fears about the measles, mumps and rubella (MMR) vaccine.
2nd person denied Ariz. transplant coverage dies
A second person denied transplant coverage by Arizona under a state budget cut has died, with this death "most likely" resulting from the coverage reduction, a hospital spokeswoman said Wednesday.
University Medical Center spokeswoman Jo Marie Gellerman said the patient died Dec. 28 at another medical facility after earlier being removed from UMC's list for a liver transplant needed because of hepatitis C.
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