Much of what medical researchers conclude in their studies is misleading, exaggerated, or flat-out wrong. So why are doctors—to a striking extent—still drawing upon misinformation in their everyday practice? Dr. John Ioannidis has spent his career challenging his peers by exposing their bad science.
But beyond the headlines, Ioannidis was shocked at the range and reach of the reversals he was seeing in everyday medical research. “Randomized controlled trials,” which compare how one group responds to a treatment against how an identical group fares without the treatment, had long been considered nearly unshakable evidence, but they, too, ended up being wrong some of the time. “I realized even our gold-standard research had a lot of problems,” he says. Baffled, he started looking for the specific ways in which studies were going wrong. And before long he discovered that the range of errors being committed was astonishing: from what questions researchers posed, to how they set up the studies, to which patients they recruited for the studies, to which measurements they took, to how they analyzed the data, to how they presented their results, to how particular studies came to be published in medical journals.
Health Glance
The FDA has said that the controversial drug Avastin should be phased out as a treatment for metastatic breast cancer. Recent studies show that its benefits are outweighed by dangerous side effects.
There's good news on the fluoride front in New York City this week, but your help is needed there (and also in San Diego). Councilor Peter Vallone is introducing a bill to the New York City Council that would end fluoridation in NYC. We need help from all our New York City readers to support this effort to protect the safety of the NYC water supply and remove this toxic chemical from the tap water there.
The doctor who linked childhood autism to a vaccine and has been branded a fraud by the British Medical Journal (BMJ) said he was the victim of a smear campaign by drug manufacturers.





























