Exposure to fluoride often results in dental fluorosis. Large numbers of U.S. young people — estimated up to 80 percent in some cities — now have dental fluorosis, the first visible sign of excessive fluoride exposure. Dental fluorosis consists of damage to tooth-forming cells, leading to a defect in tooth enamel. It is also an indicator of fluoride damage to bones.
Story on Mystery Substance Distracts from Fact Fluoride is a Deadly Killer
Novartis drugs fail to help high-risk patients
The Novartis diabetes drug Starlix failed to reduce progression to the disease or cut down on serious heart problems in patients at high risk for both diabetes and heart disease, according to a large study released on Sunday. The 9,306-patient study tested Starlix, known chemically as nateglinide, and the big-selling Novartis blood pressure medicine Diovan.
Diovan, known chemically as valsartan, reduced progression to diabetes by 14 percent compared to a placebo but failed to reduce the risk of serious heart problems, such as heart attack and stroke, according to researchers who presented the data at the American College of Cardiology scientific meeting in Atlanta.
The failure of Starlix to provide benefit to these patients and lack of heart impact by Diovan came as a surprise to researchers.
Federal Vaccine Court Rules Against Autism Families
Government's Refusal to Fund Sound Science Stacks Deck Against Vaccine-Injured Children and Casts Doubt on the Integrity of the National Immunization Program says SafeMinds.
WASHINGTON, March 12 /PRNewswire-USNewswire/ -- Autism and mercury advocacy organization SafeMinds regrets today's ruling by the U.S. Court of Federal Claims against three families who argued that vaccines which contained the mercury-based preservative thimerosal contributed to their child's autism. The denial of reasonable compensation to families was based on inadequate vaccine safety science and poorly designed and highly controversial epidemiology studies supported by the Centers for Disease Control and Prevention.
Long-Term Use of Osteoporosis Drugs Linked to Fractures
Long-term use of oral drugs prescribed to keep osteoporosis at bay may be associated with unusual fractures of the thigh bone, two new studies suggest.
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The research is not the first to link the drugs, known as bisphosphonates, with unusual fractures. Other research has found pros and cons, with the drugs reducing breast cancer risk but increasing the risk of painful jaw problems.
"Bisphosphonates are a good first start," said study co-author, Dr. Melvin Rosenwasser, a professor of orthopedic surgery at Columbia University College of Physicians and Surgeons in New York City. "Used beyond a certain point, yet to be determined, they may actually be bad."
Painkillers may increase risk of hearing loss
Regular use of aspirin, acetaminophen and other analgesics appears to substantially increase the risk of hearing loss, especially in men younger than 50.
Researchers reported recently in the American Journal of Medicine that use of acetaminophen more than twice a week by such men doubles the risk of hearing loss, use of ibuprofen and related non-steroidal anti-inflammatory drugs (NSAIDs) increases the risk by nearly two-thirds, and regular use of aspirin increases it by about a third.
Studies in animals and anecdotal reports in humans have indicated that high doses of the analgesics could interfere with hearing, but there have been few studies looking at regular use and none studying acetaminophen (one brand name is Tylenol), according to the study authors.
Researchers: AIDS virus can hide in bone marrow
The virus that causes AIDS can hide in the bone marrow, avoiding drugs and later awakening to cause illness, according to new research that could point the way toward better treatments for the disease. Finding that hide-out is a first step, but years of research lie ahead.
Dr. Kathleen Collins of the University of Michigan and her colleagues report in this week's edition of the journal Nature Medicine that the HIV virus can infect long-lived bone marrow cells that eventually convert into blood cells.
Vitamin D 'triggers and arms' the immune system
Scientists at the University of Copenhagen have discovered that Vitamin D is crucial to activating our immune defences and that without sufficient intake of the vitamin, the killer cells of the immune system – T cells – will not be able to react to and fight off serious infections in the body.
For T cells to detect and kill foreign pathogens such as clumps of bacteria or viruses, the cells must first be ‘triggered’ into action and "transform" from inactive and harmless immune cells into killer cells that are primed to seek out and destroy all traces of invaders. The researchers found that the T cells rely on vitamin D in order activate and they would remain dormant, ‘naïve’ to the possibility of threat if vitamin D is lacking in the blood.
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