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Long-Term Use of Osteoporosis Drugs Linked to Fractures

Long-term use of oral drugs prescribed to keep osteoporosis at bay may be associated with unusual fractures of the thigh bone, two new studies suggest.
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The research is not the first to link the drugs, known as bisphosphonates, with unusual fractures. Other research has found pros and cons, with the drugs reducing breast cancer risk but increasing the risk of painful jaw problems.

"Bisphosphonates are a good first start," said study co-author, Dr. Melvin Rosenwasser, a professor of orthopedic surgery at Columbia University College of Physicians and Surgeons in New York City. "Used beyond a certain point, yet to be determined, they may actually be bad."

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Painkillers may increase risk of hearing loss

Regular use of aspirin, acetaminophen and other analgesics appears to substantially increase the risk of hearing loss, especially in men younger than 50.

Researchers reported recently in the American Journal of Medicine that use of acetaminophen more than twice a week by such men doubles the risk of hearing loss, use of ibuprofen and related non-steroidal anti-inflammatory drugs (NSAIDs) increases the risk by nearly two-thirds, and regular use of aspirin increases it by about a third.

Studies in animals and anecdotal reports in humans have indicated that high doses of the analgesics could interfere with hearing, but there have been few studies looking at regular use and none studying acetaminophen (one brand name is Tylenol), according to the study authors.

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Researchers: AIDS virus can hide in bone marrow

The virus that causes AIDS can hide in the bone marrow, avoiding drugs and later awakening to cause illness, according to new research that could point the way toward better treatments for the disease. Finding that hide-out is a first step, but years of research lie ahead.

Dr. Kathleen Collins of the University of Michigan and her colleagues report in this week's edition of the journal Nature Medicine that the HIV virus can infect long-lived bone marrow cells that eventually convert into blood cells.

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Vitamin D 'triggers and arms' the immune system

Scientists at the University of Copenhagen have discovered that Vitamin D is crucial to activating our immune defences and that without sufficient intake of the vitamin, the killer cells of the immune system – T cells – will not be able to react to and fight off serious infections in the body.

For T cells to detect and kill foreign pathogens such as clumps of bacteria or viruses, the cells must first be ‘triggered’ into action and "transform" from inactive and harmless immune cells into killer cells that are primed to seek out and destroy all traces of invaders. The researchers found that the T cells rely on vitamin D in order activate and they would remain dormant, ‘naïve’ to the possibility of threat if vitamin D is lacking in the blood.

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Recalls: McCormick mixes, spinach dips, soup

The following recalls have been announced: McCormick & Company is recalling certain best buy and product codes of McCormick French Onion dip mix, McCormick vegetable dip mix, McCormick onion gravy mix and McCormick corn bread stuffing.

They could be contaminated with salmonella, an organism that can cause serious and sometimes fatal infections in young children and others with weakened immune systems. No illnesses have been reported, the company said.

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Fluoride Poisons Children in Jharkhand, India

Fluoride poisoning from groundwater in India's eastern state of Jharkhand is causing serious health problems for villagers.

In Chukru village the people are suffering from acute dental and skeletal disorders, and it's been that way for a long time.

Yellowed teeth and bone deformities develop as soon as children reach the age of five.

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Salmonella-based food flavoring recall is spreading

An unfolding recall of a commonly used flavoring ingredient found in a wide variety of foods could ripple through the entire food industry, experts say. Four companies have recalled products linked to possible salmonella contamination since Feb. 26. Two were announced Wednesday and one Thursday. Given the broad use of ingredient, more are likely to come.

The product is called hydrolyzed vegetable protein, or HVP. Made by Basic Food Flavors of North Las Vegas, Nev., it is used in many processed foods.

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