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FDA approves Zepbound, a new obesity drug that will take on Wegovy

FDA approves Zepbound, new weight loss drug

An obesity drug called Zepbound won approval for use in adults from the Food and Drug Administration Wednesday, ushering in a new rival to Novo Nordisk's blockbuster Wegovy.

Eli Lilly & Co., maker of Zepbound, says it shows greater weight loss at a lower list price than Wegovy. The Lilly drug will be available in the U.S. by the end of the year. A version of the shot, known generically as tirezepatide, is already sold as Mounjaro to treat Type 2 diabetes.

The Lilly drug works by acting on two hormone receptors in the brain, including one called GLP-1, short for glucagon-like peptide-1 – that regulate appetite and metabolism.

The new class of medicines for managing obesity that includes Zepbound and Wegovy has given people with obesity and overweight a potent option for treatment. But the drugs are expensive, and many people who lose weight regain it after stopping the medicines.

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US chemical industry likely spent $110m trying to thwart PFAS legislation, study finds

Chem industry spent $110m to stop legislation

The US chemical industry likely spent over $110m during the last two election cycles deploying lobbyists to kill dozens of pieces of PFAS legislation and slow administrative regulation around “forever chemicals”, a new analysis of federal lobbying documents has found.

The industry’s onslaught was effective: only eight pieces of legislation that targeted PFAS made it through Congress, the paper prepared by the Food and Water Watch (FWW) nonprofit found.

“There’s an extreme amount of money that’s going into fighting [PFAS legislation],” said Amanda Starbuck, FWW’s research director and the lead author on the report. “It’s hard to win these fights when there’s so much funding being put in from the opposing side.”

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Women denied abortions file lawsuits in Idaho, Tennessee and Oklahoma over bans

Women denied abortions sues statesAn abortion rights advocacy group filed lawsuits in three states on Tuesday on behalf of women who say they were denied abortions despite suffering life-threatening pregnancy complications.

The Center for Reproductive Rights sued on behalf of eight women and four doctors in Idaho, Tennessee and Oklahoma, three states that have passed some of the strictest abortion bans since the U.S. Supreme Court gutted federal abortion rights by overturning Roe v. Wade in 2022.

The lawsuits follow a similar case brought by the center in Texas, where a judge last month sided with five women who were denied abortions and exempted women experiencing pregnancy complications from Texas' stringent abortion ban.

The lawsuits in Idaho and Tennessee ask the state courts to clarify those states' legal exceptions for abortions in cases of medical emergencies, so that doctors may perform abortions when they deem them necessary without fear of prosecution.

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These experimental brain implants can restore speech to paralyzed patients

New technology for speech for paralyzed patients

For Pat Bennett, 68, every spoken word is a struggle.

Bennett has amyotrophic lateral sclerosis (ALS), a degenerative disease that has disabled the nerve cells controlling her vocal and facial muscles. As a result, her attempts to speak sound like a series of grunts.

But in a lab at Stanford University, an experimental brain-computer interface is able to transform Bennett's thoughts into easily intelligible sentences, like, "I am thirsty," and "bring my glasses here."

The system is one of two described in the journal Nature that use a direct connection to the brain to restore speech to a person who has lost that ability. One of the systems even simulates the user's own voice and offers a talking avatar on a computer screen.

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‘Silent killer’: experts warn of record US deaths from extreme heat

Heat deaths

The punishing heatwaves that have scorched much of the US could result in a record number of heat-related deaths this year, experts have warned, amid a spike in hospitalizations from collapsing workers.

Among those needing hospital treatment are heat-exhausted hikers and even people who have suffered severe burns from touching blistering concrete and asphalt.

Heat is the leading weather-related cause of mortalities in the US, outpacing deaths from hurricanes by a factor of eight to one, and this summer’s record-breaking temperatures, worsened by the human-caused climate crisis, have led to fears a new annual high death toll will be set in 2023.

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Backers Of Ohio Abortion Rights Amendment Say They Have Enough Signatures For Ballot

Ohio backers of abortion rights have number for ballot

Advocates for abortion rights in Ohio say they’ve submitted nearly twice the number of signatures required to put a measure on the ballot enshrining abortion access in the state’s constitution.

Ohioans United for Reproductive Rights, the umbrella group behind the effort, submitted more than 700,000 signatures to the Ohio Secretary of State’s office, which will now determine whether at least 413,487 of those signatures are legitimate. If enough are valid, voters will decide on the matter in Ohio’s general election in November.

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Clumps of 5,000-mile seaweed blob bring flesh-eating bacteria to Florida

Flesh eating bacteria in FloridaIt might have been one of Alfred Hitchcock’s fanciful tales of the supernatural: a 5,000-mile wide blob of murky seaweed creeping menacingly across the Atlantic before dumping itself along the US shoreline.

But now giant clumps of the 13m-ton morass labeled the Great Atlantic sargassum belt are washing up on Florida’s beaches, scientists are warning of a real-life threat from the piles of decomposing algae, namely high levels of the flesh-eating Vibrio bacteria lurking in the vegetation.

The alarming discovery by marine biologists at Florida Atlantic University (FAU) lends a dangerous new aspect to the brown seaweed onslaught, which is already threatening to spoil the state’s busy summer tourism season as coatings of decaying goop exude a pungent aroma akin to that of rotting eggs.

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